There is potential name confusion with this species since it was formerly considered to be a subspecies of O. hirtellus (Oplismenus hirtellus subsp. setarius) The Florida Plant Atlas indicates that Oplismenus setarius is common in Florida. O. hirtellus (not the subspecies) has been documented from only one Florida county, and it is a non-native. This is a low groundcover that can be effective seasonally as a low-use turf in shady locations.

Naturalistic woodland landscapes.

It's paint-chip white and brown-green bark provides winter interest. The natural range is from  north Florida into southern Canada.  This species has been planted well south of its range and is occasionally collected from places (such as the median of I-75, near old homesites,  and near mine reclaimation areas) where it likely got there due to man's activities.  It has also been widely planted in mined areas. Frequently used as a yard tree or as a shade tree in parks. Best used where its large size won't overwhelm the surroundings.

This is a rare plant that should not be disturbed in the wild. Could be used as a border along sandy paths or walkways or as a foundation plant.

While it is related to chestnuts, its not generally subject to chestnut blight, and if it gets it, will likely recover. Natural settings as a small shade tree or large shrub.

While this tree has a limited native distribution in Florida, it also occurs as far west as Texas in similar types of settings. Shade tree. Can be used as a street tree. Yellow fall color.