Listed as Threatened by the Florida FDACS. Host plant for mahogony mistletoe,Phoradendron rubrum, which is listed as Endangered by the Florida FDAS. There are reports that this tree is becoming invasive in southern Florida in some areas beyond its natural range. Street tree. Yard and park shade tree.

Coral honeysuckle's bark exfoliates. Climbs by twining Given a trellis or fence this plant makes a great hedge. It can also make a good groundcover though it will not bloom as well as it does with support. Expect this plant to be evergreen in most of Florida but deciduous in colder areas.

Don't confuse this native with the non-native tropical or scarlet milkweed (Asclepias curassavica), that is often sold in big box stores, which has red and yellow flowers. Wet wildflower garden.

Not salt tolerant of inundation by salty or brackish water. Low/no tolerance of salty wind or direct salt spray

Typically not used in landscape settings. However, if appropriate management can be provided (fire), then seed-bearing plants have considerable landscape value; non-seed-bearing plants are good groundcover. For an interesting article on this plant see the Florida Wildflower Foundation blog. Restoration areas. Naturalistic landscapes.