In a 2020 study of salt in irrigation water (https://journals.ashs.org/hortsci/view/journals/hortsci/55/7/article-p1119.xml), this species was found to be moderately tolerants of salt (at concentrations considered to be brackish) in the rooting medium.  Plant survival and health were better at lower salt concentrations.  Salt wind tolerance was based on known occurrences of this plant in near-shore, open areas near the east coast of Florida. Informal garden planting.

Its more upland relative, Nyssa sylvatica, grows well in sandy uplands and is highly similar in appearance. Somewhat slow growing. Grows naturally in swamps and best planted in moist areas. For moist settings, it is appropriate both as a shade tree and as a fall-color specimen tree in those parts of the state that get good fall cooling.

Wildflower garden, most species prefer relatively moist conditions.

The range extends from Texas to North Carolina mostly in the coastal plan and adjacent areas of sandy hills.  In Florida, the range is continuous down to central Florida and then peters out, a pattern that largely corresponds to climate (temperature patterns).  This species should grow well from the central peninsula northward. Can be used as a specimen plant, hedge (can be trimmed), shelter plant, or wildlife thicket. Appreciated for its shiny dark foliage.