While it is related to chestnuts, its not generally subject to chestnut blight, and if it gets it, will likely recover. Natural settings as a small shade tree or large shrub.

There is potential name confusion with this species since it was formerly considered to be a subspecies of O. hirtellus (Oplismenus hirtellus subsp. setarius) The Florida Plant Atlas indicates that Oplismenus setarius is common in Florida. O. hirtellus (not the subspecies) has been documented from only one Florida county, and it is a non-native. This is a low groundcover that can be effective seasonally as a low-use turf in shady locations.

USF Plant Atlas location in Hillsborough appears to have been from seed in imported soil - the one in St. Lucie County has been removed from the FLAS database (likely it was an error). The Institute for Regional Conservation reports the species to be extirpated in Florida  though it is occasionally cultivated, potentially from imported plants.  Images provided here are from a specimen cultivated by Roger Hammer. Use as a specimen plant.

For special uses only. This tall growing vine can hide unsightly objects in moist places and is useful to providing cover for wildlife and food for birds. When grown on a fence or arbor, new leaves can be bright red in color.

Retain if in the landscape. Can be used as a specimen plant in areas not subject to root disturbance.

Naturalistic woodland landscapes.

Depending on cold, this may keep its leaves all year or die back during the winter. In colder areas, consider growing it as an annual. It adapts well to semi-shady to shady well-drained conditions. Herbarium specimens from Marion and Alachua counties were in disturbed "garden" localities - not mapped here.  Not planted, but highly unlikely to have appeared other than through human disturbance. Used as a ground cover, one of the relatively few Florida plants that both forms a low dense cover and survives shade.

This is a rare plant that should not be disturbed in the wild. Could be used as a border along sandy paths or walkways or as a foundation plant.

Restoration of savannas. Curiosity in the wildflower garden.

Interesting silky-looking foliage. Tallish groundcover in mesic (moist) areas. Can be planted in groupings in shady areas. Despite the name, the leaves are pretty, almost silky or velvety in appearance.

Closely related plants occur in the Caribbean and Central America. Yellow or orange flowering plants are not the Florida native. In recent years plants have been found growing wild near homesites in north Florida -- what you plant can escape into the wild if planted beyond the natural range. Please plant responsibly - this plant has the potential to be invasive when used outside of its natural range.   Please act responsibly. Specimen or hedge plant. Also works well in informal background thickets.

Flowers range from maroon to maroon and white, to maroon and green mixed. One common name is gopherberry - because golpher tortoise eat the fruit. Specimen plant.